100ug, PDGFbb, Animal-free Recombinant Human PDGFbb

Animal-free Recombinant Human PDGFbb isa growth factor that promotes blood vessel formation, mitogenesis, chemotaxis, etc. The PDGF family members (four homodimers and one heterodimer) are secreted, disulfide-linked dimeric glycoproteins that regulate their cellular functions through interaction with PDGFR receptors. PDGFbb is synthesized, stored, and released by alpha granules of platelets. It is also known as PDGF-2, becaplermin, or GDGF. Dysregulation in PDGF signaling has been shown to be associated with tumorigenesis and progression of cancer. Recombinant PDGFbb is used in treatment of chronic ulcers and to speed healing in surgical procedures.

Storage conditions:

Lyophilized proteins are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

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